Validation of NMR fingerprinting methods: effects of processing on measure reproducibility and laboratory performance assessment

Temporary interception and then re-infusion of oxygenated blood into heart during on-pump Coronary Artery Bypass Grafting (CABG) surgery causes ischemia-reperfusion injury (IRI). Propofol is an intravenous anesthetic agent that maybe potentially cardioprotective against IRI. This thesis presents the development, validation and application of analytical methods for monitoring propofol and a Flow injection electrospray–mass spectrometry (FIE–MS) is finding utility as a first-pass metabolite fingerprinting tool in many research fields. We provide a protocol that has proved reliable

Assessment of performance by statistical analysis may not be appropriate for qualitative examinations. ⎯ In interpretive tests, the “proficiency testing item” is a test result (e.g. a descriptive morphology statement), a set of data (e.g. to determine a calibration line) or other set of information (e.g. a case study), concerning an interpretative feature of the participant's competence.

Validation of NMR fingerprinting methods: effects of processing on measure reproducibility and laboratory performance assessment. L'opera scientifica di un fisico eretico del XX secolo. Dalle leggi di conservazione alla teoria della relativit

Mar 9, 2016 ... This has led to a lack of validated analytical methods for dietary ... with use of bioassays related to the hypothesized clinical effect (4–6). ... Examples of classes of phytochemicals measured as part of product ... by which a method's performance is assessed for its fitness for purpose, precision, and accuracy.

Aug 8, 2018 ... NMR spectroscopy is a technology that is widely used in ... flexible and reproducible automatic metabolite profiling in 1D 1H-NMR datasets. ... chemical shift– from every quantified signal) for further evaluation. ... Materials and Methods ... The original study analysed 1H-NMR fingerprint data, with the help of  ...