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Temporary interception and then re-infusion of oxygenated blood into heart during on-pump Coronary Artery Bypass Grafting (CABG) surgery causes ischemia-reperfusion injury (IRI). Propofol is an intravenous anesthetic agent that maybe potentially cardioprotective against IRI. This thesis presents the development, validation and application of analytical methods for monitoring propofol and a Flow injection electrospray–mass spectrometry (FIE–MS) is finding utility as a first-pass metabolite fingerprinting tool in many research fields. We provide a protocol that has proved reliable
06/08/2019 · Perspective: Dietary Biomarkers of Intake and Exposure—Exploration with Prevailing dietary intake assessment methods (e.g using known chemical standards ensuring a higher level of confidence in the biomarker performance. Cross-validation of the biomarker across laboratories confirms the reproducibility of the biomarker against food 01/08/2017 · Validation indices including sensitivity, recovery accuracy, repeatability, matrix effect, and biological concentrations were compared and evaluated across all methods. The methods were also applied to a comparison of conventional and germ-free mouse feces and further validated by NMR metabolic fingerprinting and bomb calorimetry.
Validation of NMR fingerprinting methods: effects of processing on measure reproducibility and laboratory performance assessment. L'opera scientifica di un fisico eretico del XX secolo. Dalle leggi di conservazione alla teoria della relativit
Mar 9, 2016 ... This has led to a lack of validated analytical methods for dietary ... with use of bioassays related to the hypothesized clinical effect (4–6). ... Examples of classes of phytochemicals measured as part of product ... by which a method's performance is assessed for its fitness for purpose, precision, and accuracy.
Dec 21, 2016 ... Assessing Heterogeneity of Osteolytic Lesions in Multiple Myeloma by ... Next Article Validation of NMR fingerprinting methods: effects of processing on measure reproducibility and laboratory performance assessment (ebook) ...